Recent developments in the field of mental health have brought attention to the potential of saffron, a spice often used in culinary traditions from the Middle East and South Asia. According to Dr. Daniel Amen, a psychiatric expert and founder of Amen Clinics based in California, there is growing evidence that saffron might be as effective as traditional antidepressants in treating symptoms of depression. The spice, which is a key ingredient in dishes such as paella, has been noted for its potential to elevate mood and support overall mental health.
Amen highlighted the findings of research that suggest saffron can significantly reduce symptoms of depression, offering a natural alternative to pharmacological treatments. The studies, including a meta-analysis published in Reviews in Clinical Medicine 2025, indicate that saffron has a moderate to large antidepressant effect, making it an intriguing option for individuals seeking non-traditional treatments for depression. In addition to improving mood, saffron has also been associated with enhanced cognitive functions, including better memory and focus, according to various research studies.
Moreover, the spice has been linked to a reduction in the symptoms of premenstrual syndrome (PMS), as observed in an 8 to 12-week study where participants reported a significant decrease in PMS-related discomfort. Dr. Amen also pointed out that saffron may help improve sexual function, which is often impacted negatively by traditional antidepressants. This dual benefit of saffron for both mood and sexual health is particularly notable, as it offers a holistic approach to mental health challenges.
While these findings are promising, experts have warned that long-term use of saffron as a supplement has not been thoroughly studied, and therefore, caution is advised. Individuals interested in incorporating saffron into their routine should consult with a healthcare professional to ensure safe and effective use. The spice is now available in various forms, such as capsules, tablets, and powdered extracts, with a typical recommended daily dose of 30 milligrams.
In addition to saffron, other natural remedies like the keto diet and red meat have been suggested to have positive impacts on mental health, according to recent studies. For those considering alternative treatments, it is essential to balance these options with professional medical advice to achieve the best possible outcomes.