French Startup Robeauté Develops Rice-Sized Microrobot for Safer Brain Surgery

French Startup Robeauté Develops Rice-Sized Microrobot for Safer Brain Surgery

A French startup named Robeauté has recently secured $29 million in funding to develop a groundbreaking microrobot for neurosurgical applications. This microrobot, measuring about three millimeters in length and roughly the size of a grain of rice, aims to revolutionize the treatment of brain tumors and other neurological conditions by offering a safer and more precise alternative to traditional surgical methods.

Current neurosurgical techniques often involve rigid instruments that can only move in straight lines, limiting the areas where surgeons can operate safely. Many tumors or problematic brain areas are too risky to access due to their proximity to critical functions like movement or speech. As a result, some tumors remain untreated, and many drugs cannot reach certain areas of the brain due to the blood-brain barrier.

The Robeauté microrobot is designed to overcome these limitations. It enters the brain through a tiny incision approximately one millimeter wide and can navigate complex brain pathways by following curved paths. The device uses rotating silicone rings at its tip to gently shift tissue without causing damage, mimicking the adhesion forces that allow tiny insects to walk on water. This innovative design allows the robot to move delicately through the brain, reducing the risk of damage to surrounding areas.

Inside the microrobot, there is a compartment housing miniature surgical tools such as a flexible needle and tiny forceps. These tools can be used for performing biopsies, implanting electrodes for conditions like Parkinson’s disease, or delivering drugs directly to tumors. The robot also features sensors that send real-time data back to the surgeon, providing critical information during the procedure.

Planning the robot’s path is another significant advancement. Using MRI scans combined with artificial intelligence, surgeons can map out safe routes that avoid sensitive brain areas. During surgery, they can adjust the robot’s position in real time using ultrasound imaging mounted on the skull, achieving sub-millimeter precision. This level of precision promises to significantly enhance the safety and effectiveness of neurosurgical procedures.

Robeauté has already conducted preclinical trials on sheep with promising results, showing no major complications like bleeding. The company plans to begin human clinical trials in 2026, initially focusing on microbiopsies of brain tumors. They also aim to expand into the U.S. market and seek FDA approval, with aspirations to launch internationally by 2030.

The potential impact of the Robeauté microrobot is substantial. It could enable earlier diagnosis of brain tumors and more effective treatment with reduced risks. The minimally invasive approach could lead to faster recovery times and fewer side effects for patients. Furthermore, the capability to collect real-time data from within the brain may accelerate research and development of treatments for neurodegenerative diseases such as Alzheimer’s and Parkinson’s.

Robeauté’s microrobot embodies a remarkable convergence of robotics, artificial intelligence, biology, and medicine. While challenges such as regulatory approvals and scaling up manufacturing processes remain, the device has the potential to transform previously untreatable brain tumors into manageable conditions. As one of the company’s founders described, the microrobot functions like a