The California Department of Health confirmed three cases of clade I mpox in Southern California, marking the first instances of community transmission without international travel history. This development has raised alarms about the potential for wider outbreaks, as the virus can now spread through direct skin-to-skin contact and intimate interactions. The cases were identified in Long Beach and Los Angeles County, with all three patients hospitalized but now in recovery. Health officials warn that although the public health risk remains low, this represents a shift toward local transmission, emphasizing the importance of vaccination and preventive measures for high-risk groups.
The California Department of Health (CDPH) has released a statement on Oct. 17, stating that there have been three confirmed cases of clade I mpox. The Department emphasized that the cases were unrelated and identified in the City of Long Beach and Los Angeles County. Dr. Rita Nguyen, the Assistant State Public Health Officer, wrote in the CDPH notice that the department will continue to monitor the situation to reduce spread, recommending that Californians should ‘stay informed and take preventive measures.’ She also highlighted the severity of clade I mpox, noting that ‘risk of severe disease and hospitalization are highest for people with weakened immune systems, so it’s critical to protect yourself by getting both doses of the mpox vaccine if you or your sex partner(s) may be at risk for mpox.’
Both clade I and II mpox can spread through intimate physical contact, including direct skin-to-skin contact with an mpox rash, scabs, or body fluids; sharing a living space or personal items with an infected person; or from a pregnant woman to a fetus or baby, according to health agencies. Casual contact, such as on an airplane, office, or store, is unlikely to spread mpox, according to the CDPH. The Department has also advised that mpox symptoms may initially mimic the flu, followed by a rash, and that the virus can be diagnosed through lab testing.
Health officials urge those exposed to mpox to get vaccinated as soon as possible, before symptoms develop, and to avoid intimate contact for 21 days. Individuals who develop symptoms should speak with their doctor immediately to undergo testing. Mpox-positive patients should isolate at home and avoid contact with others until the rash is healed. CDPH reiterated that the public health risk remains low, but the emergence of community transmission is a significant development that requires ongoing monitoring and public education to prevent further spread.